Understanding others: a pilot investigation of cognitive and affective facets of social cognition in patients with 22q11.2 deletion syndrome (22q11DS)
Autor: | Deborah Myriam Badoud, Maude Schneider, Martin Debbané, Stephan Eliez, Bronwyn Glaser, Sarah Menghetti |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Male
Emotions Pilot Projects Developmental psychology ddc:616.89 0302 clinical medicine Cognition ddc:150 Theory of mind Social functioning Child education.field_of_study Neuropsychology Social cognition Adolescence Social Perception Female Psychology Clinical psychology Adult Psychosis Adolescent Cognitive Neuroscience Population Pathology and Forensic Medicine lcsh:RC321-571 03 medical and health sciences Young Adult medicine DiGeorge Syndrome Humans education Social Behavior lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Research Perspective (graphical) medicine.disease Vineland Adaptive Behavior Scale 030227 psychiatry Affect 22q11.2 deletion syndrome Pediatrics Perinatology and Child Health Neurology (clinical) Emotion recognition Perspective taking 030217 neurology & neurosurgery |
Zdroj: | Journal of Neurodevelopmental Disorders, Vol 9, Iss 1, Pp 1-9 (2017) Journal of Neurodevelopmental Disorders Journal of Neurodevelopmental Disorders, Vol. 9, No 1 (2017) P. 35 |
ISSN: | 1866-1955 1866-1947 |
Popis: | Background Although significant impairments in the affective and cognitive facets of social cognition have been highlighted in patients with 22q11.2 deletion syndrome (22q11DS) in previous studies, these domains have never been investigated simultaneously within the same group of participants. Furthermore, despite theoretical evidence, associations between these two processes and schizotypal symptoms or social difficulties in this population have been scarcely examined. Methods Twenty-nine participants with 22q11DS and 27 typically developing controls (N = 5 siblings; N = 22 unrelated controls) aged between 11 and 21 years participated in the study. Both groups were matched for age and gender distribution. Two computerized social cognition tasks evaluating perspective and emotion recognition abilities were administered to all participants. The levels of schizotypal trait expression and social functioning were further investigated in both groups, based on a validated self-report questionnaire (Schizotypal Personality Questionnaire) and parental interview (Vineland Adaptive Behavior Scales). Results Participants with 22q11DS exhibited lower perspective-taking and emotion recognition capacities than typically developing controls. The two socio-cognitive dimensions investigated here were further correlated in healthy controls. The efficiency of perspective-taking processes (response time) was marginally related to the degree of schizotypal trait expression in patients with 22q11DS. Conclusions This study first provides support for significant deficits in two core facets of social cognition in 22q11DS. The associations observed between the experimental tasks and measures of social functioning or schizotypal symptoms in 22q11DS open promising research avenue, which should be more deeply investigated in future studies. |
Databáze: | OpenAIRE |
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