Motor nerve conduction studies on children with spinal muscular atrophy
| Autor: | Yoshihiro Takeuchi, Masaharu Ochi, Kiyoshi Hirai, Akira Nishimura, Tadashi Sawada, Syouji Kawase, Yuri Miyanomae |
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| Rok vydání: | 1996 |
| Předmět: |
Male
Neural Conduction Spinal Muscular Atrophies of Childhood Nerve conduction velocity Pathogenesis Muscular Atrophy Spinal medicine Humans Tibial nerve Child Motor Neurons business.industry Infant Newborn Electromyoneurography Infant Spinal muscular atrophy Anatomy medicine.disease SMA Median nerve Median Nerve Electrophysiology Pediatrics Perinatology and Child Health Female Tibial Nerve business |
| Zdroj: | Acta paediatrica Japonica : Overseas edition. 38(6) |
| ISSN: | 0374-5600 |
| Popis: | Median and posterior tibial motor nerve conduction studies were performed on 10 children with spinal muscular atrophy (SMA). Three patients with SMA type I, in whom rapid deterioration occurred, showed reduced motor nerve conduction velocity and a remarkably low M-wave amplitude in both nerves. In type II and III patients, the motor nerve conduction velocity was normal in the median nerve, although the M-wave amplitude was small in the tibial nerve. In four patients, a reduction of the M-wave amplitude was observed as clinical symptoms advanced. These findings may suggest that motor conduction studies in spinal muscular atrophy provide complementary information for understanding the pathogenesis and are also useful to clarify the heterogeneity of this disease. |
| Databáze: | OpenAIRE |
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