Spontaneous retinal pigment epithelium tear in geographic atrophy

Autor: Eric H Souied, Giuseppe Querques, Federico Corvi, E. Cavallero, Francesco Bandello
Přispěvatelé: Cavallero, E, Corvi, F, Souied, E, Bandello, Francesco, Querques, Giuseppe
Rok vydání: 2016
Předmět:
Zdroj: Journal Français d'Ophtalmologie. 39:64-68
ISSN: 0181-5512
DOI: 10.1016/j.jfo.2015.05.010
Popis: Purpose. - To report two cases of spontaneous retinal pigment epithelial (RPE) tears occurring in two patients affected with geographic atrophy (GA) due to non-exudative age-related macular degeneration (AMD). Case report. - Two patients (a 79-year-old man and a 71-year-old woman) presented to our department with progressive visual loss. The man had a best-corrected visual acuity (BCVA) of 20/100 in the right eye (RE) and 20/50 in the left eye (LE); the woman had a BCVA of 20/200 in the RE and 20/160 in the LE. Upon complete ophthalmologic examination, revealing a large area of atrophy (> 175 mu m in diameter) along with pigmentary changes, calcified drusen and no choroidal neovascularization (CNV) in either eye, the patients were diagnosed with GA due to non-exudative AMD. Interestingly, the imaging modalities performed, including fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (SD-OCT), clearly highlighted the presence of spontaneous RPE tears in the context of non-exudative AMD, while in general, RPE tears are a well-recognized complication of exudative AMD. Conclusions. - To our knowledge, this is the first description of spontaneous RPE tears as a possible complication of GA due to non-exudative AMD. (C) 2015 Elsevier Masson SAS. All rights reserved. OI Corvi, Federico/0000-0002-2661-5500 Purpose. - To report two cases of spontaneous retinal pigment epithelial (RPE) tears occurring in two patients affected with geographic atrophy (GA) due to non-exudative age-related macular degeneration (AMD). Case report. - Two patients (a 79-year-old man and a 71-year-old woman) presented to our department with progressive visual loss. The man had a best-corrected visual acuity (BCVA) of 20/100 in the right eye (RE) and 20/50 in the left eye (LE); the woman had a BCVA of 20/200 in the RE and 20/160 in the LE. Upon complete ophthalmologic examination, revealing a large area of atrophy (> 175 mu m in diameter) along with pigmentary changes, calcified drusen and no choroidal neovascularization (CNV) in either eye, the patients were diagnosed with GA due to non-exudative AMD. Interestingly, the imaging modalities performed, including fluorescein angiography (FA), indocyanine green angiography (ICGA) and spectral-domain optical coherence tomography (SD-OCT), clearly highlighted the presence of spontaneous RPE tears in the context of non-exudative AMD, while in general, RPE tears are a well-recognized complication of exudative AMD. Conclusions. - To our knowledge, this is the first description of spontaneous RPE tears as a possible complication of GA due to non-exudative AMD. (C) 2015 Elsevier Masson SAS. All rights reserved.
Databáze: OpenAIRE