Action observation and imitation in autism spectrum disorders: an ALE meta-analysis of fMRI studies
| Autor: | Jie Yang, Jessica Hofmann |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Cingulate cortex
Autism Spectrum Disorder Cognitive Neuroscience Motion Perception behavioral disciplines and activities 050105 experimental psychology 03 medical and health sciences Behavioral Neuroscience Cellular and Molecular Neuroscience 0302 clinical medicine mental disorders medicine Humans 0501 psychology and cognitive sciences Radiology Nuclear Medicine and imaging Mirror neuron medicine.diagnostic_test 05 social sciences Neuropsychology Brain Inferior parietal lobule medicine.disease Imitative Behavior Magnetic Resonance Imaging Dorsolateral prefrontal cortex Psychiatry and Mental health medicine.anatomical_structure Neurology Autism Neurology (clinical) Psychology Functional magnetic resonance imaging Neuroscience Insula 030217 neurology & neurosurgery |
| Zdroj: | Brain imaging and behavior. 10(4) |
| ISSN: | 1931-7565 |
| Popis: | Previous studies have shown that the mirror neuron system (MNS) plays an important role in action understanding. However, whether and how the MNS activity is different in individuals with autism spectrum disorders (ASD) and typically developed (TD) individuals are still unclear. The current study used activation likelihood estimation to conduct a meta-analysis of functional magnetic resonance imaging studies that investigated action observation and imitation in ASD and TD individuals. Thirteen studies were selected, and the contrasts focused on the brain effects in ASD and TD participants and the differences between the two groups. The results showed that compared with TD individuals, ASD individuals exhibited stronger effects in the anterior inferior parietal lobule, a part of the putative human MNS. In addition, the ASD group demonstrated altered effects in the occipital cortex, dorsolateral prefrontal cortex, cingulate cortex, and insula. These results suggest that ASD individuals demonstrate dysfunction of the MNS during action observation and imitation. Furthermore, brain regions involved in visual processing, executive function, and social cognitive function might also show dysfunction during action task performance. |
| Databáze: | OpenAIRE |
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