Medication Review in Preventing Older Adults’ Fall-Related Injury: a Systematic Review & Meta-Analysis
| Autor: | Yu Ming, Susan W. Hunter, Aleksandra Zecevic, Rommel G. Tirona, Wenxin Miao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Medication review
medicine.medical_specialty Psychological intervention CINAHL Systemic Review Meta-Analysis prevention Intervention (counseling) falls Injury prevention Medicine medication review older adults fall-related injuries business.industry Prevention Absolute risk reduction Fall-related injuries Data extraction Older adults Meta-analysis Physical therapy Falls Geriatrics and Gerontology business Gerontology |
| Zdroj: | Canadian Geriatrics Journal Paediatrics Publications |
| ISSN: | 1925-8348 |
| Popis: | Background Medication review is essential in managing adverse drug reactions and improving drug safety in older adults. This systematic review evaluated medication review’s role as a single intervention or combined with other interventions in preventing fall-related injuries in older adults. Methods Electronic databases search was conducted in PubMed, EMBASE, Scopus, and CINAHL. Two reviewers screened titles and abstracts, reviewed full texts, and performed data extraction and risk of bias assessment. Meta-analyses were conducted on studies with similar participants, interventions, outcomes or settings. Results Fourteen randomized, controlled studies were included. The pooled results indicated that medication review as a stand-alone intervention was effective in preventing fall-related injuries in community-dwelling older adults (Risk Difference [RD] = -0.06, 95% CI: [-0.11, -0.00], I2 = 61%, p = .04). Medication review also had a positive impact on decreasing the risk of fall-related fractures (RD = -0.02, 95% CI: [-0.04, -0.01], I2 = 0%, p = .01). Discussion This systematic review and meta-analysis has demonstrated that medication review is effective in preventing fall-related injuries in general, and fractures specifically, in community-dwelling older adults. Future investigations focusing on the process of performing medication review will further inform fall-related injury prevention for older adults. |
| Databáze: | OpenAIRE |
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