Therapeutic misadventure with paracetamol in children
| Autor: | Malathi Sathiyasekeran, Kuruvilla Thomas, So Shivbalan |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
paracetamol Short Communication Analgesic Context (language use) Pharmacology Early initiation medicine Pharmacology (medical) Antipyretic Intensive care medicine Acetaminophen Liver injury NAC business.industry Therapeutic misadventure digestive oral and skin physiology toxicity medicine.disease therapeutic misadventure N-acetylcysteine poisoning Over-the-counter business medicine.drug |
| Zdroj: | Indian Journal of Pharmacology |
| ISSN: | 1998-3751 |
| Popis: | Paracetamol (acetaminophen), though considered a safe, “over the counter” analgesic and antipyretic, can cause liver injury with overdose. Therapeutic misadventure is a unique problem where the existing nomogram used for acute poisoning is not applicable. In this context, early initiation of N-acetylcysteine even before a biochemical evidence of liver injury may be beneficial. A series of 6 children with this type of paracetamol overdose are presented here to increase the awareness and understanding of this problem since no such data is available from India. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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