A new novel method for assessing intracranial pressure using non-invasive fundus images: a pilot study

Autor:	Christian Bonde Pedersen, Frantz Rom Poulsen, Mikkel Schou Andersen
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Intracranial Pressure Fundus Oculi Video Recording lcsh:Medicine Pilot Projects Fundus (eye) Likelihood ratios in diagnostic testing Article 03 medical and health sciences 0302 clinical medicine Arteriole medicine.artery Image Processing Computer-Assisted Medicine Humans In patient Eye manifestations lcsh:Science Intracranial pressure Multidisciplinary Venule medicine.diagnostic_test business.industry Non invasive lcsh:R Fundus photography ROC Curve Area Under Curve Neurological manifestations 030221 ophthalmology & optometry Linear Models lcsh:Q business Nuclear medicine 030217 neurology & neurosurgery Software
Zdroj:	Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020) Andersen, M S, Pedersen, C B & Poulsen, F R 2020, ' A new novel method for assessing intracranial pressure using non-invasive fundus images : a pilot study ', Scientific Reports, vol. 10, 13062 . https://doi.org/10.1038/s41598-020-70084-0 Scientific Reports
ISSN:	2045-2322
DOI:	10.1038/s41598-020-70084-0
Popis:	Arteriole and venule diameter ratio (A/V-ratio) can be measured using fundus photography. In this pilot study, we correlated changes in the intracranial pressure with the diameter of vessels of the retina. We investigated whether increased intracranial pressure (ICP) was reflected in a measurable and quantifiable distention of the venule diameter, leading to a decreased A/V-ratio. This was demonstrated by assessment of the A/V-ratio in patients already undergoing conventional ICP monitoring with a cerebral intraparenchymal pressure monitor. Our method shows a correlation between A/V ratio and ICP and suggests an easily obtainable and usable point-of-care (POC), non-invasive method to estimate the intracranial pressure without the necessity of mydriatic drugs. Furthermore, the sensitivity/specificity analysis with a cut-off of
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99c71b8e676dcfd431e5bc5f7a6f8b0 http://link.springer.com/article/10.1038/s41598-020-70084-0 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.