Short-term neuropsychological outcome following Gamma Knife radiosurgery for arteriovenous malformations: a preliminary report
| Autor: | Jonathan E. Hodes, Lee X. Blonder, John D. Ranseen, Frederick A. Schmitt |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Adult
Intracranial Arteriovenous Malformations Male medicine.medical_treatment Gamma knife radiosurgery Neuropsychological Tests Radiosurgery Lateralization of brain function Functional Laterality Cognition Postoperative Complications Preliminary report Developmental and Educational Psychology medicine Humans medicine.diagnostic_test business.industry Neuropsychology Magnetic resonance imaging General Medicine Neuropsychological test Middle Aged Radiation therapy Neuropsychology and Physiological Psychology Treatment Outcome Female business Nuclear medicine After treatment |
| Zdroj: | Applied neuropsychology. 6(3) |
| ISSN: | 0908-4282 |
| Popis: | This study investigated the effect of Gamma Knife radiosurgery for the treatment of arteriovenous malformations (AVMs) on neuropsychological functioning. We examined neuropsychological performance in 10 patients before and after radiosurgical treatment with the Leksell cobalt-60 Gamma Knife unit. The patients included 7 right-handed women and 3 right-handed men. Three patients had left hemisphere AVMs, 4 had right hemisphere AVMs, and 3 had midline AVMs. Each patient was given neuropsychological testing within 1 week before Gamma Knife radiosurgery. Testing was repeated an average of 11.4 months after treatment. There were no statistically significant differences between pre- and postradiosurgical neuropsychological test scores on any measure. Pretreatment AVM diameter as measured on magnetic resonance scans ranged from 1.6 to 6.5 cm. After treatment, 2 AVMs disappeared, 4 decreased slightly in size, and 4 remained unchanged. We conclude that Gamma Knife radiotherapy in this sample of patients was neither detrimental nor beneficial to neuropsychological functioning. |
| Databáze: | OpenAIRE |
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