Effect of Probenecid on the Blood Levels and Urinary Excretion of Cefamandole
Autor: | H. R. Black, G. L. Brier, R. S. Griffith, J. D. Wolny |
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Rok vydání: | 1977 |
Předmět: |
Adult
Male Time Factors medicine.drug_class Antibiotics Cephalosporin Urine Pharmacology Excretion Urinary excretion medicine Humans Drug Interactions Pharmacology (medical) Cefamandole Probenecid Chemistry Middle Aged Pharmacology and Therapeutics Cephalosporins Infectious Diseases Mandelic Acids medicine.drug Beta lactam antibiotics |
Zdroj: | Antimicrobial Agents and Chemotherapy. 11:809-812 |
ISSN: | 1098-6596 0066-4804 |
DOI: | 10.1128/aac.11.5.809 |
Popis: | Two oral 0.5-g doses of probenecid given 7 and 1 h before a single 1-g intramuscular dose of cefamandole resulted in higher serum levels of cefamandole than when cefamandole was given alone: 37 versus 20 μg per ml of serum, respectively. Cefamandole was not measurable ( |
Databáze: | OpenAIRE |
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