Effect of Hypophysectomy on Immunocytochemically Demonstrated Gonadotropin-Releasing Hormone in the Rat Brain
| Autor: | Burton L. Baker, W C Dermody |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
endocrine system
Pituitary gland medicine.medical_specialty Hypophysectomy medicine.drug_class medicine.medical_treatment Hypothalamus Gonadotropin-releasing hormone Biology Gonadotropin-Releasing Hormone Endocrinology Internal medicine medicine Animals Brain Chemistry Lamina terminalis Histocytochemistry Median Eminence Pituitary Hormone-Releasing Hormones Nerve Regeneration Rats medicine.anatomical_structure Median eminence Magnocellular cell Female Gonadotropin hormones hormone substitutes and hormone antagonists |
| Zdroj: | Endocrinology. 98:1116-1122 |
| ISSN: | 1945-7170 0013-7227 |
| DOI: | 10.1210/endo-98-5-1116 |
| Popis: | The objective was to determine the effect of hypophysectomy on the store of gonadotropin-releasing hormone (GnRH) in certain parts of the brain as revealed by immunocytochemistry. The antiserum used was prepared against synthetic GnRH conjugated with limpet hemocyanin. No change was observed in the store of GnRH in the organum vasculosum of the lamina terminalis or in the cephalic segment of the median eminence GnRH was depleted severely from the central and caudal (junction with the infundibular stem) segments of the median eminence. GnRH was not found in the axons of magnocellular neurons that regenerate during repair of the median eminence-pituitary stalk after hypophysectomy. |
| Databáze: | OpenAIRE |
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