The effect of preoperative embolization on surgical outcomes for carotid body tumor resection
| Autor: | Garth T. Olson, LeAnn Chavez, Robin Osofsky, Nathan H. Boyd, Ross M. Clark, Muhammad Ali Rana, Sundeep Guliani, John Marek, Mark Langsfeld, Jaideep Das Gupta |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
lcsh:R5-920 business.industry cranial nerve injury Tumor resection General Medicine 030204 cardiovascular system & hematology Shamblin classification Surgery 03 medical and health sciences Preoperative embolization 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Cranial Nerve Injury medicine preoperative embolization Carotid body Original Research Article business lcsh:Medicine (General) Carotid body tumor high-altitude |
| Zdroj: | SAGE Open Medicine, Vol 9 (2021) SAGE Open Medicine |
| ISSN: | 2050-3121 |
| Popis: | Objective: Compare the effects of preoperative embolization for carotid body tumor resection on surgical outcomes to carotid body tumor resections without preoperative embolization. Methods: Single-center retrospective review of all consecutive patients who underwent carotid body tumor resection from 2001 to 2019. Surgical outcomes with emphasis on operative time (estimated blood loss and cranial nerve injury) of patients undergoing carotid body tumor resection following preoperative embolization were compared to those undergoing resection alone using unpaired Student’s t-test and Fisher’s exact test. Results: Forty-six patients (15% male, mean age 50 ± 15 years) underwent resection of 49 carotid body tumors. Patients undergoing preoperative embolization ( n = 20 (40%)) had larger mean tumor size (4.0 ± 0.7 vs 3.2 ± 1 cm, p = 0.006), increased Shamblin II/III tumor classification (18 (90%) vs 22 (76%), p Conclusion: After controlling for tumor Shamblin classification and size, carotid body tumor resections following preoperative embolization were associated with increased operative time and inferior surgical outcomes compared to those tumors undergoing resection alone. Nonetheless, such results remain susceptible to the confounding effects of individual tumor characteristics often used in the decision to perform preoperative embolization, underscoring the need for prospective studies evaluating the utility of preoperative embolization for carotid body tumors. |
| Databáze: | OpenAIRE |
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