Alkoxyl Radicals Generated under Photoredox Catalysis: A Strategy for anti‐Markovnikov Alkoxylation Reactions
| Autor: | Guillaume Dagousset, Emmanuel Magnier, Béatrice Tuccio, Anne-Laure Barthelemy |
|---|---|
| Přispěvatelé: | Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
Spin trapping Chemistry Alkene 010405 organic chemistry Radical Markovnikov's rule Photoredox catalysis Ether General Chemistry General Medicine 010402 general chemistry Combinatorial chemistry 01 natural sciences Catalysis 0104 chemical sciences Williamson ether synthesis chemistry.chemical_compound [CHIM]Chemical Sciences Alkyl |
| Zdroj: | Angewandte Chemie International Edition Angewandte Chemie International Edition, Wiley-VCH Verlag, 2018, 57 (42), pp.13790--13794. ⟨10.1002/anie.201806522⟩ Angewandte Chemie International Edition, 2018, 57 (42), pp.13790--13794. ⟨10.1002/anie.201806522⟩ |
| ISSN: | 1521-3757 0044-8249 1433-7851 1521-3773 |
| Popis: | WOS:000446826200010; Reported herein is a novel photoredox-catalyzed approach for ether synthesis and it involves alkoxyl radicals generated from N-alkoxypyridinium salts. A wide range of alkenes are smoothly difunctionalized in an anti-Markovnikov fashion, affording various functionalized alkyl alkyl ethers. Notably, this mild process tolerates a number of functional groups and is efficiently carried out under both batch and flow conditions. Importantly, electron paramagnetic resonance (EPR) experiments by spin trapping were carried out to characterize the radical intermediates involved in this radical/cationic process. |
| Databáze: | OpenAIRE |
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