Anatomy and nomenclature of tree shrew lymphoid tissues
| Autor: | Nan Shi, Hua Li, Wei Xia, Yi-wei Feng, An-zhou Tang, Ketong Ji, He Guangyao |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Submandibular lymph nodes
Tupaia General Veterinary Axillary lymph nodes Iliac Lymph Node Thoracic cavity Lymphoid Tissue Tupaiidae Spleen General Medicine Anatomy Biology General Biochemistry Genetics and Molecular Biology medicine.anatomical_structure Cervical lymph nodes Models Animal medicine Animals Animal Science and Zoology Lymph Lymph node |
| Zdroj: | Experimental animals. 71(2) |
| ISSN: | 1881-7122 |
| Popis: | The immune response plays a key role in the disease development of the organism, while immune function serves as an important indicator for animal models evaluation. The tree shrew (Tupaia belangeri chinensis), as a new laboratory animal with a close genetic relationship with primates, has been used to construct various disease models. However, the immune system of tree shrews, especially anatomical descriptions of lymph nodes, is still relatively unknown. In this study, a total of 16 different lymph nodes were identified, including superficial lymph nodes and deep lymph nodes. Superficial lymph nodes were located in the head and neck region (submandibular lymph node, parotid lymph node, deep and superficial cervical lymph nodes) and at the forelimb (axillary and accessory axillary lymph nodes, subscapular lymph node) and hindlimb (popliteal, sciatic, and inguinal lymph nodes). Deep lymph nodes comprise mediastinal lymph nodes located in thoracic cavity and abdominal lymph nodes that are mainly located in each mesentery (mesenteric, gastric, pancreatic-duodenal, renal lymph nodes) or along the major vessels (iliac lymph nodes). In addition, we described the spleen and thymus of the tree shrew, as well as two lymphoid tissues in the top wall of the nasal cavity and the oropharynx. This study mainly describes the tree shrew immune system from an anatomical and histopathological perspective and provides fundamental research references for the establishment of various animal models of tree shrews. |
| Databáze: | OpenAIRE |
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