Acute Abdomen and Lupus Enteritis: Thrombocytopenia and Pneumatosis Intestinalis as Indicators for Surgery

Autor:	F, Alcocer-Gouyonnet, C, Chan-Nuñez, J, Hernández, J, Guzmán, A, Gamboa-Domínguez
Rok vydání:	2000
Předmět:	Abdomen Acute Serositis Adolescent Intestinal Perforation Humans Lupus Erythematosus Systemic Female General Medicine Pneumatosis Cystoides Intestinalis Thrombocytopenia Enteritis
Zdroj:	Scopus-Elsevier
ISSN:	1555-9823 0003-1348
Popis:	Bowel symptoms occur often in systemic lupus erythematosus (SLE), but enteric complications in patients on steroid therapy are rare. We report a case of a 14-year-old Mexican girl with SLE on high-dose steroid therapy complicated by abdominal vasculitis and small bowel perforation. Accompanying this serious complication were thrombocytopenia and radiographic changes of pneumatosis intestinalis. These findings suggested necrotizing enteritis and prompted urgent surgery. Four jejunal perforations, pneumatosis intestinalis, and submucosal vasculitis were present in the resected specimen. Persistent SLE activity responded to cyclophosphamide, which is indicated in patients with digestive symptoms who fail to respond to high-dose steroids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98a2e51895fa3ed82cd862f125ae7ae https://doi.org/10.1177/000313480006600216 Zobrazit plný text záznamu