Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT
| Autor: | Jacqueline A.E. Langius, P.A.M. van Leeuwen, B.S. van der Meij, Egbert F. Smit, S.M. Slootmaker, Marieke D. Spreeuwenberg, Marinus A. Paul |
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| Přispěvatelé: | Internal medicine, Epidemiology and Data Science, Public and occupational health, Surgery, Pulmonary medicine, ICaR - Circulation and metabolism, CCA - Quality of life, Health Services Research, RS: CAPHRI School for Public Health and Primary Care |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Health Status Medicine (miscellaneous) Gastroenterology law.invention Cognition Quality of life Randomized controlled trial law Carcinoma Non-Small-Cell Lung Activities of Daily Living chemistry.chemical_classification Nutrition and Dietetics Hand Strength Middle Aged n-3 fatty acids Eicosapentaenoic acid Combined Modality Therapy Eicosapentaenoic Acid Docosahexaenoic acid Female Original Article Dietary Proteins RCT Polyunsaturated fatty acid medicine.medical_specialty Docosahexaenoic Acids Motor Activity lung neoplasms Affect (psychology) Double-Blind Method Internal medicine Fatty Acids Omega-3 Carcinoma medicine Humans Interpersonal Relations Lung cancer Aged Neoplasm Staging business.industry medicine.disease eicosapenaenoic acid chemistry quality of life Physical Fitness Dietary Supplements Physical therapy business Energy Intake |
| Zdroj: | European Journal of Clinical Nutrition European Journal of Clinical Nutrition, 66(3), 399-404. Nature Publishing Group van der Meij, B S, Langius, J A E, Spreeuwenberg, M D, Slootmaker, S M, Paul, M A, Smit, E F & van Leeuwen, P A M 2012, ' Oral nutritional supplements containing n-3 polyunsaturated fatty acids affect quality of life and functional status in lung cancer patients during multimodality treatment: an RCT ', European Journal of Clinical Nutrition, vol. 66, no. 3, pp. 399-404 . https://doi.org/10.1038/ejcn.2011.214 |
| ISSN: | 1476-5640 0954-3007 |
| DOI: | 10.1038/ejcn.2011.214 |
| Popis: | Background/Objectives: Our objective was to investigate effects of an oral nutritional supplement containing n-3 polyunsaturated fatty acids (FAs) on quality of life, performance status, handgrip strength and physical activity in patients with non-small cell lung cancer (NSCLC) undergoing multimodality treatment. Subjects/Methods: In a double-blind experiment, 40 patients with stage III NSCLC were randomised to receive 2 cans/day of a protein- and energy-dense oral nutritional supplement containing n-3 polyunsaturated FAs (2.02 g eicosapentaenoic acid+0.92 g docosahexaenoic acid/day) or an isocaloric control supplement, during multimodality treatment. Quality of life, Karnofsky Performance Status, handgrip strength and physical activity (by wearing an accelerometer) were assessed. Effects of intervention were analysed by generalised estimating equations. P-values |
| Databáze: | OpenAIRE |
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