Post-influenzal triazole-resistant aspergillosis following allogeneic stem cell transplantation

Autor:	Ruairi J. Fahy, Larry Bacon, Eimear Ann Joyce, Jacques F. Meis, Brian O'Connell, Thomas R. Rogers, Alida Fe Talento, Katie Dunne, Elisabeth Vandenberge, Grace Chan, Ferry Hagen, Niamh Murphy
Přispěvatelé:	Westerdijk Fungal Biodiversity Institute, Westerdijk Fungal Biodiversity Institute - Medical Mycology
Rok vydání:	2018
Předmět:	0301 basic medicine Male Antifungal Agents 030106 microbiology Triazole Drug Resistance Homologous/adverse effects Dermatology Aspergillus fumigatus/drug effects Transplantation Homologous/adverse effects Aspergillosis Virus Aspergillus fumigatus 03 medical and health sciences chemistry.chemical_compound Drug Resistance Fungal Influenza Human medicine Stem Cell Transplantation/adverse effects Transplantation Homologous Humans Risk factor skin and connective tissue diseases Invasive Pulmonary Aspergillosis/diagnosis Invasive Pulmonary Aspergillosis Transplantation Triazoles/pharmacology biology business.industry General Medicine Invasive pulmonary aspergillosis Triazoles Human/complications Middle Aged biology.organism_classification medicine.disease Influenza Infectious Diseases lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Fungal chemistry Immunology Antifungal Agents/pharmacology Stem cell business Influenza Human/complications Stem Cell Transplantation
Zdroj:	Mycoses, 61, 570-575 Mycoses, 61, 8, pp. 570-575 Mycoses, 61(8), 570-575. John Wiley and Sons Ltd
ISSN:	0933-7407
Popis:	Item does not contain fulltext Influenza virus infection is now recognised as a risk factor for invasive pulmonary aspergillosis (IPA). Delays in diagnosis contribute to delayed commencement of antifungal therapy. In addition, the emergence of resistance to first-line triazole antifungal agents puts emphasis on early detection to prevent adverse outcomes. We present 2 allogeneic stem cell transplant patients who developed IPA due to triazole-resistant Aspergillus fumigatus following influenza infection. We underline the challenges faced in the management of these cases, the importance of early diagnosis and need for surveillance given the emergence of triazole resistance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a988f104da9f901982a35cbf3f083cfc https://hdl.handle.net/2066/196657 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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