Response to steroids in Budd-Chiari syndrome caused by idiopathic granulomatous venulitis
| Autor: | Aubrey Groll, Paul N. Manley, Jerome B. Simon, Robert N. Clark, Iain D. Young |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Adult
Male Vasculitis Pathology medicine.medical_specialty Budd-Chiari Syndrome Hepatic Veins Necrosis Thrombotic occlusion Prednisone Ascites medicine Humans Granuloma Hepatology Hepatic vein thrombosis medicine.diagnostic_test business.industry Liver Diseases Gastroenterology medicine.disease Liver Liver biopsy Budd–Chiari syndrome Portal hypertension medicine.symptom Differential diagnosis business medicine.drug |
| Zdroj: | Gastroenterology. 94:503-507 |
| ISSN: | 0016-5085 |
| DOI: | 10.1016/0016-5085(88)90444-1 |
| Popis: | A 31-yr-old man presented with the Budd-Chiari syndrome. A liver biopsy specimen demonstrated noncaseating centrilobular granulomas and an idiopathic necrotizing granulomatous venulitis involving hepatic vein radicles with superimposed thrombotic occlusion. High-dose prednisone therapy produced dramatic clinical improvement with resolution of the hepatomegaly, ascites, and portal hypertension and normalization of the hepatic venous angiogram. A repeat liver biopsy specimen showed resolution of the venulitis and disappearance of the hepatic vein thrombosis. Idiopathic granulomatous venulitis that is reversible with prednisone therapy should be considered in the differential diagnosis of the Budd-Chiari syndrome. |
| Databáze: | OpenAIRE |
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