Granulocyte transfusions for patients with severe thermal burns
| Autor: | R. D. Workman, R. M. Jager, J. J. McCullough, R. G. Strate, Paul G. Quie, R. J. Faville |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Immunology Antibiotics Enterobacter Granulocyte medicine.disease_cause Sepsis Internal medicine Klebsiella medicine Immunology and Allergy Humans Blood Transfusion Young adult Pseudomonas aeruginosa business.industry Hematology medicine.disease Surgery Ecthyma gangrenosum Chemotaxis Leukocyte Leukocyte Transfusion medicine.anatomical_structure Single episode business Burns Granulocytes |
| Zdroj: | Transfusion. 18(2) |
| ISSN: | 0041-1132 |
| Popis: | Ten severely burned (>50% BSA) pediatric and young adult patients developed 19 episodes of clinical sepsis of four or more days duration. During eight of the 19 septic episodes the patients received granulocyte transfusions (median, four; range, two to seven). Risk variables, types and prevalence of infections, mainly Pseudomonas aeruginosa and antibiotic regimens were similar for all the septic episodes studied. All eight episodes (100 per cent) resolved in the transfused group while eight of 11 (72 per cent) episodes resolved in the nontransfused group. Patients survived four episodes of ecthyma gangrenosum when granulocyte transfusions were used and the single episode in which they were not used was fatal. Granulocyte transfusions may he helpful in severely burned patients with sepsis. |
| Databáze: | OpenAIRE |
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