beta.-Lactam antibiotics with N-oxide side chains. 1. Quinoxaline N-oxides
| Autor: | Ronald E. Bambury, H. W. Ritter, M. L. Edwards |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Staphylococcus aureus
Chemistry Oxide Microbial Sensitivity Tests Penicillins Medicinal chemistry Cyclic N-Oxides Penicillin Mice chemistry.chemical_compound Quinoxaline Salmonella paratyphi B Quinoxalines Pseudomonas aeruginosa Drug Discovery medicine Side chain Animals Molecular Medicine Pseudomonas Infections Proteus Infections Antibacterial activity Proteus mirabilis Beta lactam antibiotics medicine.drug |
| Zdroj: | Journal of Medicinal Chemistry. 19:330-333 |
| ISSN: | 1520-4804 0022-2623 |
| DOI: | 10.1021/jm00224a026 |
| Popis: | A series of penicillin derivatives of quinoxaline di-N-oxide carboxylic acids was prepared. These compounds were prepared from the acid chlorides and mixed anhydrides of the quinoxaline di-N-oxides. The compounds prepared exhibited minimal antibacterial activity against gram-negative organisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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