Chemosensory signaling controls motility and subcellular polarity in Myxococcus xanthus
| Autor: | David R. Zusman, Christine Kaimer, James E. Berleman |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Myxococcus xanthus biology Gliding motility Chemotaxis Cell Polarity Motility biology.organism_classification Microbiology Protein subcellular localization prediction Article Pilus Cell biology Transport protein Protein Transport Infectious Diseases Bacterial Proteins Cell polarity Locomotion Signal Transduction |
| Zdroj: | Current Opinion in Microbiology. 15:751-757 |
| ISSN: | 1369-5274 |
| Popis: | Myxococcus xanthus is a model system for the study of dynamic protein localization and cell polarity in bacteria. M. xanthus cells are motile on solid surfaces enabled by two forms of gliding motility. Motility is controlled by the Che-like Frz pathway, which is essential for fruiting body formation and differentiation. The Frz signal is mediated by a GTPase/GAP protein pair that establishes cell polarity and directs the motility systems. Pilus driven motility at the leading pole of the cell requires dynamic localization of two ATPases and the coordinated production of EPS synthesis. Gliding motility requires dynamic movement of large protein complexes, but the mechanism by which this system generates propulsive force is still an active area of investigation. |
| Databáze: | OpenAIRE |
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