Atypical propylthiouracil-induced ANCA-positive vasculitis: report of a case with unusual clinical and histopathologic findings
| Autor: | Jason F. Solus, Amy Musiek, Jamie L. Mull, Ilana S. Rosman, Herbert C Chiang, Misha M Mutizwa |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Cytopenia
medicine.medical_specialty Pathology business.industry Antithyroid agent medicine.medical_treatment Graves' disease Dermatology General Medicine medicine.disease Pancytopenia Prednisone hemic and lymphatic diseases medicine Histopathology propylthiouracil ANCA vasculitis vasculopathy Propylthiouracil business Vasculitis medicine.drug |
| Zdroj: | Mull, Jamie L; Solus, Jason F; Mutizwa, Misha M; Chiang, Herbert C; Rosman, Ilana S; & Musiek, Amy. (2015). Atypical propylthiouracil-induced ANCA-positive vasculitis: report of a case with unusual clinical and histopathologic findings. Dermatology Online Journal, 21(8). Retrieved from: http://www.escholarship.org/uc/item/3v22b88d |
| Popis: | Author(s): Mull, Jamie L; Solus, Jason F; Mutizwa, Misha M; Chiang, Herbert C; Rosman, Ilana S; Musiek, Amy | Abstract: The side effects of propylthiouracil, including cytopenia and vasculitis, are well established. We present an interesting case in which cytopenia and cutaneous vasculopathy occurred concomitantly in a critically ill patient. The patient was initially treated for suspected infection until dermatologic and rheumatologic workup revealed ANCA-positivity and vasculopathy on histopathology, most consistent with an atypical presentation of ANCA-positive vasculitis. Upon initiation of immunosuppressive therapy, the patient’s condition rapidly improved emphasizing the importance of early recognition of this condition. |
| Databáze: | OpenAIRE |
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