Histochemical demonstration of heavy metals in mouse skin
| Autor: | Najma A. Janjua, Toshifumi Itano, Li Jin, Tetuhide H. Murakami |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Silver Staining
Pathology medicine.medical_specialty Histology Connective tissue chemistry.chemical_element Zinc Sulfides Mice Dermis medicine Animals Chelation Coloring Agents Hematoxylin Chelating Agents Skin Dose-Response Relationship Drug Staining and Labeling integumentary system Chemistry Heavy metals Cell Biology General Medicine Staining medicine.anatomical_structure Connective Tissue Metals Mouse skin Eosine Yellowish-(YS) Epidermis Ditiocarb Hair |
| Zdroj: | Acta Histochemica. 97:383-388 |
| ISSN: | 0065-1281 |
| Popis: | Summary The localization of heavy metals in normal mouse skin was investigated lightmicroscopically using the Neo-Timm staining method. Positive staining was found in the horny layer of epidermis, connective tissue of dermis and in hair roots. Chelation of heavy metals by pretreatment with diethyldithiocarbamate prevented this staining. The study demonstrates that heavy metals, mainly zinc, are localized in the mouse skin and that the Neo-Timm staining method is useful for the investigation of the role of zinc in this organ. |
| Databáze: | OpenAIRE |
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