Pulmonary sarcomatoid carcinoma mimicking pleural mesothelioma
| Autor: | Xing Chen, Maoli Liang, Jie Cao, Shuo Li, Le Wang, Jing Zhang, Wei Zhou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Mesothelioma medicine.medical_specialty Lung Neoplasms Pleural Neoplasms Chest pain Diagnosis Differential Biopsy medicine Humans biopsy Clinical Case Report Lung cancer Sarcomatoid carcinoma Lung medicine.diagnostic_test business.industry Carcinoma Mesothelioma Malignant General Medicine Middle Aged medicine.disease medicine.anatomical_structure immunohistochemistry histopathology Histopathology pulmonary sarcomatoid carcinoma Radiology Differential diagnosis medicine.symptom pleural mesothelioma business Brain metastasis Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Introduction: Pulmonary sarcomatoid carcinoma (PSC) is an extremely rare biphasic tumor characterized by a mixture of malignant epithelial and mesenchymal cells. Owing to the rarity, as well as the lack of typical manifestations and imaging signs, the rate of misdiagnosis is high. Herein, we present a case of PSC misdiagnosed as pleural mesothelioma in a 59-year-old man. Patient concerns: A 59-year-old man presented with recurrent coughing, fever, and chest pain. Diagnosis: Chest computed tomography showed 2 large and dense masses involving the inferior lobes of right lung, along with slight irregular pleural thickening and a small amount of effusion. Interventions: Chest computed tomography-guided tumor biopsy was performed. PSC was confirmed based on histopathology and immunohistochemistry. The patient refused treatment due to economic reasons. Outcomes: The patient developed adrenal, multiple lung and brain metastasis. The overall survival time was 11 months. Conclusions: PSC, despite its rarity, should be considered in the differential diagnosis of lung cancer. Besides, biopsy, histopathology, and specific immunohistochemical staining of larger tissue specimens can be contributing to the accurate diagnosis of PSC. |
| Databáze: | OpenAIRE |
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