Brachial plexus block with a new local anaesthetic: 0.5 percent ropivacaine

Autor: S M Raza, Janna Blanchard, Joan Hoffman, Somayaji Ramamurthy, Rosemary Hickey, Zia Durrani, Kenneth D. Candido, Alon P. Winnie, R. W. Masters
Rok vydání: 1990
Předmět:
Zdroj: Canadian Journal of Anaesthesia. 37:732-738
ISSN: 1496-8975
0832-610X
DOI: 10.1007/bf03006530
Popis: A new local anaesthetic, ropivacaine hydrochloride, was used in a concentration of 0.5 per cent in 32 patients receiving a subclavian perivascular block for upper extremity surgery. One group (n = 15) received 0.5 per cent ropivacaine without epinephrine and a second group (n = 17) received 0.5 per cent ropivacaine with epinephrine in a concentration of 1:200,000. Anaesthesia was achieved in 87 per cent of the patients in both groups in all of the C5 through T1 brachial plexus dermatomes. Motor block was profound with 100 per cent of patients in both groups developing paresis at both the shoulder and hand and 100 per cent developing paralysis at the shoulder. There was a rapid initial onset of sensory block (a mean of less than four minutes for analgesia) with a prolonged duration (a mean of greater than 13hr of analgesia). The addition of epinephrine did not significantly affect the quality or onset of sensory or motor block. The duration of sensory block was reduced by epinephrine at T1 for analgesia and at C7, C8, and T1 for anaesthesia. The duration of sensory block in the remaining brachial plexus dermatomes as well as the duration of motor block was not effected by epinephrine. There was no evidence of cardiovascular or central nervous system toxicity in either group with a mean dose of 2.5– 2.6 mg · kg− 1 ropivacaine.
Databáze: OpenAIRE
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