Exploring the potent inhibitors and binding modes of phospholipase A2 through in silico investigation
| Autor: | Shafi Mahmud, Nurul Absar, Zannati Ferdous Zaoti, Yasir Mohamed Riza, Sanjida Alam, Md. Rimon Parves, Suvendu Ray, Khaled Mahmud Sujon, Fahmida Alam Tithi |
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| Rok vydání: | 2019 |
| Předmět: |
chemistry.chemical_classification
Binding Sites biology Chemistry Naja In silico Proteolytic enzymes General Medicine Molecular Dynamics Simulation biology.organism_classification complex mixtures Phospholipases A2 Enzyme Phospholipase A2 Biochemistry Structural Biology Snake venom biology.protein Thermodynamics lipids (amino acids peptides and proteins) Molecular Biology Snake Venoms |
| Zdroj: | Journal of Biomolecular Structure and Dynamics. 38:4221-4231 |
| ISSN: | 1538-0254 0739-1102 |
| DOI: | 10.1080/07391102.2019.1680440 |
| Popis: | Snake venom of Naja naja comprises of several types of enzymes, and among them, water-soluble proteolytic enzyme, phospholipase A2 (PLA2), is noteworthy for its numerous adverse effects, such as cy... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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