Increased lead absorption with anemia and slowed nerve conduction in children near a lead smelter
| Autor: | Kenneth V. Eden, Walter A. Orenstein, Edward L. Baker, Ian H. von Lindern, John A. Mather, Philip J. Landrigan, Robert G. Feldman, Anthony J. Yankel, Dennis H. Cox |
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| Rok vydání: | 1976 |
| Předmět: |
Male
Anemia Erythrocyte protoporphyrin Idaho Lead absorption Neural Conduction Protoporphyrins Mineralogy Lead poisoning Animal science medicine Humans Child Air Pollutants Dose-Response Relationship Drug Health consequences business.industry Infant Lead smelting medicine.disease Lead Poisoning Hematocrit Lead Child Preschool Pediatrics Perinatology and Child Health Toxicity Epidemiologic Methods Nerve conduction business |
| Zdroj: | The Journal of Pediatrics. 89:904-910 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(76)80594-x |
| Popis: | Studies to evaluate the prevalence, sources, and health consequences of lead absorption were conducted among children living near a primary lead smelter. Lead levels in air, soil, and dust were highest at the smelter and decreased with distance. Ninety-nine percent of one- to nine-year-old children living within 1.6 kilometers had blood lead levels greater than or equal 40 mug/dl, indicating increased absorption, and 22% had levels greater than or equal 80 mug/dl. The prevalence of lead levels greater than or equal 40 mug/dl decreased with distance; at 72 kilometers from the smelter it was 1%. Erythrocyte protoporphyrin levels increased with blood lead levels: 17% of children with lead levels of greater than or equal 80 mug/dl were anemic. There was no overt neurologic toxicity. Significant negative correlation was found in 202 five- to nine-year-old children between blood lead levels and motor nerve conduction velocity (r = 0.38, p less than 0.02). |
| Databáze: | OpenAIRE |
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