A meta-analysis reveals temperature, dose, life stage, and taxonomy influence host susceptibility to a fungal parasite
| Autor: | Bryan K. Delius, Brittany F. Sears, Sarah A. Knutie, Jason R. Rohr, Matthew D. Venesky, David J. Civitello, Scott M. Bessler, Nicole Ortega, Marc J. Lajeunesse, Neal T. Halstead, Taegan A. McMahon, Suzanne Young, Erin L. Sauer, Jeremy M. Cohen, Elizabeth A. Roznik, Karena H. Nguyen |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Batrachochytrium dendrobatidis Zoology Biology Experimental laboratory 010603 evolutionary biology 01 natural sciences 03 medical and health sciences Animals Parasite hosting Parasites Chytridiomycosis Ecology Evolution Behavior and Systematics 030304 developmental biology 0303 health sciences Larva Ecology 010604 marine biology & hydrobiology Temperature Pathogenic fungus biology.organism_classification Life stage Chytridiomycota Mycoses Meta-analysis Taxonomy (biology) Anura |
| DOI: | 10.1101/818377 |
| Popis: | Complex ecological relationships, such as host-parasite interactions, are often modeled with laboratory experiments. However, some experimental laboratory conditions, such as temperature or infection dose, are regularly chosen based on convenience or convention and it is unclear how these decisions systematically affect experimental outcomes. Here, we conducted a meta-analysis of 58 laboratory studies that exposed amphibians to the pathogenic fungusBatrachochytrium dendrobatidis(Bd) to better understand how laboratory temperature, host life stage, infection dose, and host species affect host mortality. We found that host mortality was driven by thermal mismatches: hosts native to cooler environments experienced greater Bd-induced mortality at relatively warm experimental temperatures and vice versa. We also found that Bd dose positively predicted Bd-induced host mortality and that the superfamilies Bufonoidea and Hyloidea were especially susceptible to Bd. Finally, the effect of Bd on host mortality varied across host life stages, with larval amphibians experiencing lower risk of Bd-induced mortality than adults or metamorphs. Metamorphs were especially susceptible and experienced mortality when inoculated with much smaller Bd doses than the average dose used by researchers. Our results suggest that when designing experiments on species interactions, researchers should carefully consider the experimental temperature, and inoculum dose, and life stage and taxonomy of the host species. |
| Databáze: | OpenAIRE |
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