Human herpesvirus-8-related Kaposi's sarcoma after liver transplantation successfully treated with cidofovir and liposomal daunorubicin
| Autor: | Roberto Manfredi, Gabriella Verucchi, Franco Trevisani, Leonardo Calza, Mauro Bernardi, Marina Tadolini, R. Giuliani, Francesco Chiodo, Pietro Andreone, Andrea Zambruni |
|---|---|
| Přispěvatelé: | Verucchi G., Calza L., Trevisani F., Zambruni A., Tadolini M., Giuliani R., Manfredi R., Andreone P., Chiodo F., Bernardi M. |
| Rok vydání: | 2005 |
| Předmět: |
Male
Daunorubicin medicine.medical_treatment LIVER TRANSPLANTATION KAPOSI'S SARCOMA HUMAN HERPES VIRUS-8 CIDOFOVIR DAUNORUBICIN Organophosphonates Liver transplantation Antiviral Agents Cytosine Immunocompromised Host chemistry.chemical_compound Humans Medicine Viremia Sarcoma Kaposi Kaposi's sarcoma Transplantation Chemotherapy Antibiotics Antineoplastic business.industry Immunosuppression Middle Aged Viral Load medicine.disease Liver Transplantation Liposomal daunorubicin Infectious Diseases chemistry Herpesvirus 8 Human Immunology Cancer research Drug Therapy Combination Sarcoma business Cidofovir medicine.drug |
| Zdroj: | Transplant Infectious Disease. 7:34-37 |
| ISSN: | 1399-3062 1398-2273 |
| DOI: | 10.1111/j.1399-3062.2005.00081.x |
| Popis: | The iatrogenic form of Kaposi's sarcoma (KS) is typically observed among transplant recipients, and the most appropriate therapeutic approach (usually including reduction of immunosuppression, specific chemotherapy, and/or administration of antiviral agents against human herpes virus-8) is still controversial. Available experiences on the effect of the anti-herpes viruses drug cidofovir provide conflicting results. Herein, we report the clinical, histological, and virological features of a liver transplant recipient successfully treated with a combined therapy of cidofovir and liposomal daunorubicin, associated with a reduction of the immunosuppressive regimen, for an advanced cutaneous and visceral KS. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|