Antimicrobial and bone-forming activity of a copper coated implant in a rabbit model
Autor: | Mohamed Elhensheri, Joachim Rychly, Hans-Georg Neumann, Cornelia Prinz |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Staphylococcus aureus Biomedical Engineering chemistry.chemical_element 02 engineering and technology Bone healing Bone Nails Biomaterials 03 medical and health sciences Coated Materials Biocompatible Osteogenesis Alloys Animals Fracture Healing Titanium Staphylococcal Infections 021001 nanoscience & nanotechnology Antimicrobial Copper Anti-Bacterial Agents Tibial Fractures 030104 developmental biology chemistry Rabbit model Female Rabbits Implant Bone forming 0210 nano-technology Biomedical engineering |
Zdroj: | Journal of Biomaterials Applications. 32:139-149 |
ISSN: | 1530-8022 0885-3282 |
Popis: | Current strategies in implant technology are directed to generate bioactive implants that are capable to activate the regenerative potential of the surrounding tissue. On the other hand, implant-related infections are a common problem in orthopaedic trauma patients. To meet both challenges, i.e. to generate a bone implant with regenerative and antimicrobial characteristics, we tested the use of copper coated nails for surgical fixation in a rabbit model. Copper acetate was galvanically deposited with a copper load of 1 µg/mm |
Databáze: | OpenAIRE |
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