Impact of a modified apical dissection during radical retropubic prostatectomy on the occurrence of positive surgical margins: a comparative study in 212 patients
| Autor: | Francis Pontonnier, Christophe Tollon, Ghislaine Escourrou, Pierre Plante, Nicolas Vazzoler, Michel Soulié, Philippe Seguin, Jean-Michel Benoit |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Urology medicine.medical_treatment Prostate cancer Prostate medicine Humans Aged Neoplasm Staging Prostatectomy business.industry Biopsy Needle Soft tissue Prostatic Neoplasms Middle Aged Neurovascular bundle medicine.disease Surgery Dissection medicine.anatomical_structure Lymph Node Excision Positive Surgical Margin business Radical retropubic prostatectomy |
| Zdroj: | Urology. 58(2) |
| ISSN: | 1527-9995 |
| Popis: | Objectives. To assess the impact of a modified technique of apical dissection during radical retropubic prostatectomy on the occurrence of positive surgical margins (PSMs). Methods. Between 1992 and 1998, 212 nonconsecutive patients with localized prostate cancer (57 T1, 155 T2) underwent radical retropubic prostatectomy and were divided into two groups: group 1, 85 patients who underwent surgery before January 1994; and group 2, 127 patients who underwent surgery with the modification of the apical dissection after January 1994. The modified technique consisted of a wide excision of periprostatic soft tissue at the apex, including the bilateral neurovascular bundles. The clinical data (age, prostate-specific antigen, clinical staging) and pathologic findings (pathologic staging, Gleason score, PSM rate) of the two groups were compared. Results. No significant difference was found between the two groups regarding the median prostate-specific antigen level (10.8 ng/mL and 9.5 ng/mL), Gleason score, and pathologic staging. Overall, the PSM rate was 53% in group 1 and 20.5% in group 2 (P |
| Databáze: | OpenAIRE |
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