Utilizing reclassification to explore characteristics and prognosis of KDIGOSCr AKI subgroups: a retrospective analysis of a multicenter prospective cohort study

Autor:	Renhua Sun, Shusheng Li, Youzhong An, Jun-Ping Qin, Xiangyou Yu, Chuanyun Qian, Erzhen Chen, Yan Kang, Xiaochun Ma, Tiehe Qin, Zhenyang He, Gui-Ying Dong, Zhenjie Hu, Yuhang Ai, Jiandong Lin, Mingyan Zhao, Jihong Zhu, Xiuming Xi, Fachun Zhou, Bin Du, Xiangyuan Cao, Li Jiang, Dawei Wu, Yuan Xu
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Male medicine.medical_specialty medicine.medical_treatment Critical Care and Intensive Care Medicine intensive care unit law.invention length of stay law Risk Factors Internal medicine medicine Humans Renal replacement therapy Stage (cooking) Prospective cohort study Survival analysis Aged Retrospective Studies business.industry Acute kidney injury General Medicine Middle Aged medicine.disease Prognosis Intensive care unit Survival Analysis mortality kdigo Diseases of the genitourinary system. Urology Renal Replacement Therapy Intensive Care Units Respiratory failure acute kidney injury Nephrology Creatinine Practice Guidelines as Topic Clinical Study Female RC870-923 business Biomarkers Kidney disease Research Article
Zdroj:	Renal Failure, Vol 43, Iss 1, Pp 1569-1576 (2021) Renal Failure article-version (VoR) Version of Record
ISSN:	1525-6049
Popis:	Background Acute kidney injury (AKI) is widespread in the intensive care unit (ICU) and affects patient prognosis. According to Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, the absolute and relative increases of serum creatinine (Scr) are classified into the same stage. Whether the prognosis of the two types of patients is similar in the ICU remains unclear. Methods According to the absolute and relative increase of Scr, AKI stage 1 and stage 3 patients were divided into stage 1a and 1b, stage 3a and 3b groups, respectively. Their demographics, laboratory results, clinical characteristics, and outcomes were analyzed retrospectively. Results Of the 345 eligible cases, we analyzed stage 1 because stage 3a group had only one patient. Using 53 or 61.88 µmol/L as the reference Scr (Scrref), no significant differences were observed in ICU mortality (P53=0.076, P61.88=0.070) or renal replacement therapy (RRT) ratio, (P53=0.356, P61.88=0.471) between stage 1a and 1b, but stage 1b had longer ICU length of stay (LOS) than stage 1a (P53
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a956d02568c5ba0449ba6632f4b70550 https://doaj.org/article/49dfc484974744768236abafd1918d4f Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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