Predicting the clinical course in hypertrophic cardiomyopathy using thallium‐201 myocardial scintigraphy
Autor: | Kiyotaka Ohshima, Shigeru Nakata, Taishi Kuwahara, Mareomi Hamada, Akiyoshi Ogimoto, Shuntaro Ikeda, Yuji Shigematsu |
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Rok vydání: | 2021 |
Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty Heart failure 030204 cardiovascular system & hematology Sudden cardiac death Lesion 03 medical and health sciences 0302 clinical medicine Original Research Articles Internal medicine Humans Medicine Original Research Article 030212 general & internal medicine Extent score business.industry Incidence (epidemiology) Myocardial Perfusion Imaging Hypertrophic cardiomyopathy Heart Atrial fibrillation Cardiomyopathy Hypertrophic medicine.disease Thallium Radioisotopes medicine.anatomical_structure Mean count change lcsh:RC666-701 Ventricle Thallium‐201 myocardial scintigraphy cardiovascular system Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business Perfusion |
Zdroj: | ESC Heart Failure, Vol 8, Iss 2, Pp 1378-1387 (2021) ESC Heart Failure |
ISSN: | 2055-5822 |
Popis: | Aims This study aimed to evaluate the changes in left ventricular remodelling with time in patients with hypertrophic cardiomyopathy (HCM) using thallium‐201 myocardial scintigraphy. Methods and results Forty‐eight patients with HCM participated in the study. The extent score (ES) and a newly devised index termed the ‘mean count change’ (MCC) were used to evaluate the myocardial perfusion defects. Using the amount of thallium‐201 uptake (TU), MCC (%) was calculated using the following formula: (last TU − initial TU)∕initial TU × 100. To confirm the site of the lesion, the left ventricle was divided into five segments: anterior, septal, inferior, lateral, and apex. Cardiovascular complications and deaths were recorded. The mean follow‐up period was 8.6 ± 2.0 years. ES increased from 17.4 ± 13.7% to 44.0 ± 22.3% (P |
Databáze: | OpenAIRE |
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