Effects of acute hypoxia on the energy status and antioxidant defense system in the blood of carp - Cyprinvs carpio L
Autor: | D Snezana Maletic, M Ratko Radojicic, V Radoslav Zikic, D Mirjana Markovic, S Zorica Saicic, S Andras Stajn, Z Sladjan Pavlovic, M Ljiljana Dragicevic-Djokovic, I Branka Ognjanovic |
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Rok vydání: | 2002 |
Předmět: |
medicine.medical_specialty
Antioxidant medicine.medical_treatment Biology medicine.disease_cause General Biochemistry Genetics and Molecular Biology Superoxide dismutase 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Carp lcsh:QH301-705.5 030304 developmental biology chemistry.chemical_classification 0303 health sciences Lipid peroxide Glutathione peroxidase Glutathione biology.organism_classification Endocrinology lcsh:Biology (General) chemistry Biochemistry Catalase 030220 oncology & carcinogenesis biology.protein General Agricultural and Biological Sciences Oxidative stress |
Zdroj: | Archives of Biological Sciences, Vol 54, Iss 1-2, Pp 11-18 (2002) |
ISSN: | 1821-4339 0354-4664 |
DOI: | 10.2298/abs0202011z |
Popis: | The influence of acute hypoxia on glucose, pyruvate, lipid peroxide (LP) reduced glutathione (GSH) concentrations and lactate level in the whole blood of carp (Cyprinus carpio L) under aquarium conditions were studied. The activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), the concentrations of ATP and ADP and ATP/ADP ratio in the red blood cells (RBCs) were analyzed. Glutathione-S-transferase (GST) activity was determined in the plasma. Our experiments showed that short-term and long-term hypoxia causes significant changes of all examined haema-tological parameters. Increased concentration of LP and increased SOD CAT and GST activities, as well as a decreased GSH-Px activity showed that under hypoxic conditions oxidative stress and RBCs damage were produced. |
Databáze: | OpenAIRE |
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