Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens
| Autor: | Moran Ra, Yardley Jp, C R Lyttle, Magid Abou-Gharbia, Ruth A. Henderson, Lee M. Greenberger, Collini, Chris P. Miller, Marzolf Jt, Bender Rh, Heather A. Harris, Tran Bd, B S Komm, Yogendra P. Kharode, Rayomand J Unwalla |
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| Rok vydání: | 2001 |
| Předmět: |
Models
Molecular Indole test Indoles Chemistry Ovariectomy Uterus Bazedoxifene acetate Organ Size Transfection Highly selective Antiestrogen Chemical synthesis Cell Line Rats Radioligand Assay Structure-Activity Relationship Estradiol Congeners Biochemistry Design synthesis Bone Density Drug Discovery Animals Molecular Medicine Structure–activity relationship Female |
| Zdroj: | Journal of Medicinal Chemistry. 44:1654-1657 |
| ISSN: | 1520-4804 0022-2623 |
| DOI: | 10.1021/jm010086m |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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