Low serum 3‐methyl histidine level is associated with aortic stiffness in maintenance hemodialysis patients
| Autor: | Yu-Hsien Lai, Yu-Li Lin, Yu-Chi Chang, Chiu-Huang Kuo, Bang-Gee Hsu, Jen-Pi Tsai, Chih-Hsien Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Hematology Maintenance hemodialysis Odds ratio Pulse Wave Analysis Gastroenterology Vascular Stiffness Renal Dialysis Nephrology Internal medicine Potential biomarkers medicine Humans Histidine In patient Aortic stiffness business Pulse wave velocity Biomarkers Muscle catabolism Subclinical infection |
| Zdroj: | Therapeutic Apheresis and Dialysis. 26:726-733 |
| ISSN: | 1744-9987 1744-9979 |
| Popis: | 3-Methylhistidine (3MH) is an indicator of muscle catabolism. Subclinical protein malnutrition is an independent predictor of aortic stiffness (AS). We aimed to study the relationship between serum 3MH level and AS among patients undergoing maintenance hemodialysis (MHD). Carotid-femoral pulse wave velocity was applied to measure AS of 110 MHD patients. Serum 3MH levels were analyzed using high-performance liquid chromatography and mass spectrometry. AS was defined as cfPWV >10 m/s. Forty-five (40.9%) patients were categorized as having AS. Multivariable logistic (odds ratio: 0.792, p |
| Databáze: | OpenAIRE |
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