The effect of bumetanide treatment on the sensory behaviours of a young girl with Asperger syndrome

Autor: Eric Lemonnier, Céline Degrez, Marine Grandgeorge, Nelle Jallot
Přispěvatelé: Grandgeorge, Marine, Centre de Ressources Autisme Bretagne, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Laboratoire de Neurosciences de Brest (LNB), Université de Brest (UBO)
Rok vydání: 2014
Předmět:
Zdroj: BMJ Case Reports
BMJ Case Reports, BMJ Publishing Group, 2014, pp.10.1136/bcr-2013-202092
ISSN: 1757-790X
DOI: 10.1136/bcr-2013-202092
Popis: Sensory behaviours were not considered as core features of autism spectrum disorders until recently. However, they constitute an important part of the observed symptoms that result in social maladjustment and are currently quite difficult to treat. One promising strategy for the treatment of these behaviours is the use of bumetanide, which was previously shown to reduce the severity of autism spectrum disorders. In this study, we proposed to evaluate sensory behaviours using Dunn's Sensory Profile after 18 months of bumetanide treatment in a 10-year-old girl with Asperger syndrome. Reported improvements covered a large range of sensory behaviours, including auditory, vestibular, tactile, multisensory and oral sensory processing. Although our results were limited to a single case report, we believe that our clinical observations warrant clinical trials to test the long-term efficacy of bumetanide to manage the sensory behaviours of people with autism spectrum disorders.
Databáze: OpenAIRE