Chemotherapy for Generalized Infantile Myofibromatosis With Visceral Involvement
| Autor: | Rene L. Galindo, Susan Y. Wu, Timothy L. McCavit, Patrick J. Leavey, Kevin B Cederberg |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Infantile myofibromatosis MEDLINE Antineoplastic Agents medicine Humans Chemotherapy business.industry Mortality rate Infant Newborn Infant Myofibromatosis Hematology medicine.disease Dermatology Vinblastine Viscera Methotrexate Oncology Vincristine Pediatrics Perinatology and Child Health Female business medicine.drug |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 37:402-405 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/mph.0000000000000132 |
| Popis: | Infantile myofibromatosis (IM) is most commonly limited to cutaneous lesions that resolve spontaneously. However, generalized IM with visceral involvement, which has a reported mortality rate as high as 73%, has been successfully treated with a combination of methotrexate and vinblastine. Here we report the further efficacy of low-dose methotrexate and vinblastine in 2 pediatric patients with IM and visceral involvement and review the literature describing chemotherapy for these patients. |
| Databáze: | OpenAIRE |
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