Paramagnetic oil emulsions as oral magnetic resonance imaging contrast agents
| Autor: | Paul C.K. Ho-Tai, King C.P. Li, Brett L. Storm, Richard J. Rolfes, Roger P. Tart, Peter G. P. Ang |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Gadolinium DTPA
Male food.ingredient Gadolinium Biomedical Engineering Biophysics Contrast Media chemistry.chemical_element Complex Mixtures Ferric Compounds Ferrous Paramagnetism food Nuclear magnetic resonance Intestine Small Organometallic Compounds medicine Animals Humans Plant Oils Radiology Nuclear Medicine and imaging Chromatography medicine.diagnostic_test Ice Cream digestive oral and skin physiology food and beverages Magnetic resonance imaging Pentetic Acid Image Enhancement Magnetic Resonance Imaging Milk chemistry Taste Vitamin B Complex Emulsion Peanut oil Ferric Emulsions Female Corn Oil Corn oil medicine.drug |
| Zdroj: | Magnetic Resonance Imaging. 8:589-598 |
| ISSN: | 0730-725X |
| DOI: | 10.1016/0730-725x(90)90136-p |
| Popis: | The combination of a paramagnetic agent with an oil emulsion can uniformly enhance the small bowel. We discovered that the entire small bowel becomes homogeneously brighter than its surroundings when imaged with all commonly utilized pulse sequences. We have tried various combinations of ferric ammonium citrate, ferrous sulfate, gadolinium-DPTA and corn oil, olive oil and peanut oil. All paramagnetic oil emulsions tested were uniformly distributed throughout the small bowel, but the enhancement effect is much stronger with the ferric ammonium citrate and gadolinium-DPTA oil emulsions. We have also developed a mixture of Geritol, corn oil, ice cream and milk, which uniformly coats the small bowel wall, has good enhancement effect, tastes good, and is nutritious. With this dietary contrast, retroperitoneal structures including the pancreas can be well delineated. We conclude that the combination of a paramagnetic agent with an oil emulsion can work as a safe and effective magnetic resonance imaging (MRI) oral contrast agent with high patient acceptance. |
| Databáze: | OpenAIRE |
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