Cloud-Based Software Architecture for Fully Automated Point-of-Care Molecular Diagnostic Device

Autor: Chan-Young Park, Jong-Dae Kim, Byeong-Heon Kil, Ji-Seong Park, Yu-Seop Kim, Mun-Ho Ryu
Rok vydání: 2021
Předmět:
Zdroj: Sensors (Basel, Switzerland)
Sensors
Volume 21
Issue 21
Sensors, Vol 21, Iss 6980, p 6980 (2021)
ISSN: 1424-8220
Popis: This paper proposes a cloud-based software architecture for fully automated point-of-care molecular diagnostic devices. The target system operates a cartridge consisting of an extraction body for DNA extraction and a PCR chip for amplification and fluorescence detection. To facilitate control and monitoring via the cloud, a socket server was employed for fundamental molecular diagnostic functions such as DNA extraction, amplification, and fluorescence detection. The user interface for experimental control and monitoring was constructed with the RESTful application programming interface, allowing access from the terminal device, edge, and cloud. Furthermore, it can also be accessed through any web-based user interface on smart computing devices such as smart phones or tablets. An emulator with the proposed software architecture was fabricated to validate successful operation.
Databáze: OpenAIRE