Prognostic factors for stage III colon cancer in patients 80 years of age and older
| Autor: | Maude Oguer, Jean-Baptiste Nousbaum, Michel Robaszkiewicz, Lucille Quénéhervé, Tiphaine Kermarrec, Mélanie Cariou, Bogdan Badic, Servane Bouzeloc |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Perineural invasion Gastroenterology Disease-Free Survival law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine Humans Medicine Stage (cooking) Survival rate Aged Neoplasm Staging Retrospective Studies Chemotherapy business.industry Proportional hazards model Mortality rate Hepatology Prognosis Chemotherapy Adjuvant 030220 oncology & carcinogenesis Colonic Neoplasms 030211 gastroenterology & hepatology business |
| Zdroj: | International Journal of Colorectal Disease. 36:811-819 |
| ISSN: | 1432-1262 0179-1958 |
| Popis: | Oncological strategies in the elderly population are debated. The objective of this study was to assess the factors predictive of poor prognosis in elderly patients with stage III colon cancer. A retrospective review of demographic, pathologic, treatment, and outcome data from 308 patients with stage III colon adenocarcinoma who had undergone surgery between 2007 and 2014 was conducted. A proportional hazards model was used to assess the association of prognostic factors with disease-free survival (DFS) and overall survival (OS). The 5-year survival rate was 34.4% (95% CI 27.1–39.8%) and Charlson comorbidity index was a significant predictor of death (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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