RECOVERY FROM IMMUNESUPPRESSION IN MICE INFECTED WITH SCHISTOSOMA JAPONICUM BY TREATMENT OF PRAZIQUANTEL
| Autor: | Keiko Kato, Masato Kawabata, Takatoshi Kobayakawa, Mitsuyoshi Kumada, Yukio Hosaka, Hiroko Asahi, Shigeo Hayashi |
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| Rok vydání: | 1987 |
| Předmět: |
Time Factors
Untreated group Physiology Hemolytic Plaque Technique Spleen Praziquantel Schistosoma japonicum General Biochemistry Genetics and Molecular Biology Mice Immune system parasitic diseases Immune Tolerance medicine Animals Parasite Egg Count biology business.industry Significant difference biology.organism_classification medicine.anatomical_structure Schistosomiasis japonica business After treatment medicine.drug |
| Zdroj: | Japanese Journal of Medical Science and Biology. 40:89-93 |
| ISSN: | 1884-2828 0021-5112 |
| DOI: | 10.7883/yoken1952.40.89 |
| Popis: | To learn the possible alteration of immune response, hemolytic plaque-forming cells (PFC) produced in the spleen of Schistosoma japonicum infected mice treated with Praziquantel and untreated group were counted. There was no significant difference in the immunesuppression percentage between the treated and untreated groups 1 and 3 weeks after treatment. In 5 weeks after treatment, however, the immunesuppression percentage in the treated mice was markedly reduced in comparison with that of the untreated group. Recovery from immunesuppression appears to be associated with elimination or impairment of adult worms. |
| Databáze: | OpenAIRE |
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