Supervised pulmonary tele-rehabilitation versus pulmonary rehabilitation in severe COPD: a randomised multicentre trial
Autor: | Jon Torgny Wilcke, Helle Frost Andeassen, Henrik Hansen, Nina S. Godtfredsen, Gerd Martinez, Anne Frølich, Theresa Bieler, Nina Beyer, Thomas Kallemose, Lisbeth Marie Østergaard, Marie Lavesen |
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Rok vydání: | 2020 |
Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty medicine.medical_treatment Walk Test Anxiety Severe copd law.invention Pulmonary Disease Chronic Obstructive exercise pulmonary rehabilitation Lower limb muscle Tele-rehabilitation Randomized controlled trial Quality of life law Forced Expiratory Volume medicine Humans Single-Blind Method Pulmonary rehabilitation Aged COPD Depression business.industry Standard treatment Rehabilitation Middle Aged medicine.disease Telemedicine Quality of Life Physical therapy Patient Compliance Female Symptom Assessment business |
Zdroj: | Hansen, H, Bieler, T, Beyer, N, Kallemose, T, Wilcke, J T, Ostergaard, L M, Frost Andeassen, H, Martinez, G, Lavesen, M, Frolich, A & Godtfredsen, N S 2020, ' Supervised pulmonary tele-rehabilitation versus pulmonary rehabilitation in severe COPD : a randomised multicentre trial ', Thorax, vol. 75, no. 5, pp. 413-421 . https://doi.org/10.1136/thoraxjnl-2019-214246 Thorax, 75(5):413-421 Thorax |
ISSN: | 1468-3296 0040-6376 |
Popis: | RationalePulmonary rehabilitation (PR) is an effective, key standard treatment for people with COPD. Nevertheless, low participant uptake, insufficient attendance and high drop-out rates are reported. Investigation is warranted of the benefits achieved through alternative approaches, such as pulmonary tele-rehabilitation (PTR).ObjectiveTo investigate whether PTR is superior to conventional PR on 6 min walk distance (6MWD) and secondarily on respiratory symptoms, quality of life, physical activity and lower limb muscle function in patients with COPD and FEV1 MethodsIn this single-blinded, multicentre, superiority randomised controlled trial, patients were assigned 1:1 to 10 weeks of groups-based PTR (60 min, three times weekly) or conventional PR (90 min, two times weekly). Assessments were performed by blinded assessors at baseline, end of intervention and at 22 weeks’ follow-up from baseline. The primary analysis was based on the intention-to-treat principle.Measurements and main resultsThe primary outcome was change in 6MWD from baseline to 10 weeks; 134 participants (74 females, mean±SD age 68±9 years, FEV1 33%±9% predicted, 6MWD 327±103 metres) were included and randomised. The analysis showed no between-group differences for changes in 6MWD after intervention (9.2 metres (95% CI: −6.6 to 24.9)) or at 22 weeks’ follow-up (−5.3 metres (95% CI: −28.9 to 18.3)). More participants completed the PTR intervention (n=57) than conventional PR (n=43) (χ2 test pConclusionPTR was not superior to conventional PR on the 6MWD and we found no differences between groups. As more participants completed PTR, supervised PTR would be relevant to compare with conventional PR in a non-inferiority design.Trial registration numberClinicalTrials.gov (NCT02667171), 28 January 2016. |
Databáze: | OpenAIRE |
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