Endemic Lassa fever in Liberia. II. Serological and virological findings in hospital patients
| Autor: | Peter B. Jahrling, Mark H. Monson, John D. Frame, Jacob E. Yalley-Ogunro |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Adolescent Fluorescent Antibody Technique Antibodies Viral medicine.disease_cause Virus Serology Lassa Fever Internal medicine Humans Medicine Hospital patients Lassa virus Lassa fever Adult patients business.industry Incidence (epidemiology) Public Health Environmental and Occupational Health General Medicine Liberia medicine.disease Virology Infectious Diseases Indirect Fluorescent Antibody Technique Parasitology business |
| Zdroj: | Transactions of the Royal Society of Tropical Medicine and Hygiene. 78:656-660 |
| ISSN: | 0035-9203 |
| DOI: | 10.1016/0035-9203(84)90232-3 |
| Popis: | Patients admitted with fever to four Liberian hospitals were tested for Lassa fever (LF) by means of the indirect fluorescent antibody technique and by virus isolation. The incidence of LF and presumptive LF among consecutive febrile adult patients was 14% and 17% in two hospitals located in the interior; no cases of LF were found among 24 consecutive patients in a hospital near the coast. In the three inland hospitals the incidence of confirmed or presumptive LF among the patients in whom the diagnosis was seriously considered varied from 13% to 36%. Lassa virus was isolated from 17 patients out of the 59 cases found in this survey. LF is a common cause of fever in northern Liberia. The diagnosis depends upon the readiness of the staff to consider the diagnosis, the collection of blood specimens at appropriate times, and the preservation of sera at sub-freezing temperatures to permit survival of active virus and its subsequent recovery in an appropriate laboratory. |
| Databáze: | OpenAIRE |
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