Design and functional testing of a novel blood pulse wave velocity sensor
Autor: | Sjoerd P. Niehof, Egbert G. Mik, Marit H. N. van Velzen, Arjo J. Loeve |
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Přispěvatelé: | Anesthesiology |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Physics
Red laser business.industry Pulse wave velocity (PWV) Maximum deviation Functional testing Biomedical Engineering Medicine (miscellaneous) Photoplethysmography (PPG) 030204 cardiovascular system & hematology Arterial stiffness Clinical Practice 03 medical and health sciences 0302 clinical medicine Optics Photoplethysmogram cardiovascular system 030212 general & internal medicine cardiovascular diseases business Pulse wave velocity Normal range Biomedical engineering circulatory and respiratory physiology |
Zdroj: | Journal of Medical Devices, 12(1) Journal of Medical Devices, 12(1):011006. The American Society of Mechanical Engineers (ASME) |
ISSN: | 1932-6181 |
Popis: | The multiphotodiode array (MPA) is a novel transmission photoplethysmography (PPG) sensor to measure pulse wave velocity (PWV) in the finger. To validate the MPA, a setup was built to generate a red laser dot traveling over the MPA with known and constant scanning velocities. These scanning velocities were chosen to include speeds at least twice as high as those found in the normal range of PWV in healthy populations and were set at 12.9, 25.8, 36, or 46.7 m/s. The aim of this study was to verify the functionality of the MPA: performing local noninvasive PWV measurements. To illustrate the applicability of the MPA in clinical practice, an in vivo pilot study was conducted using the flow-mediated dilation (FMD) technique. The in vitro accuracy of the MPA was ±0.2%, 0.3%, 0.5%, and 0.6% at the applied scanning velocities. The MPA can measure PWVs with a maximum deviation of 3.0%. The in vivo pilot study showed a PWV before the FMD of 1.1±0.2 m/s. These results suggest that this novel MPA can reliably and accurately measure PWV within clinically relevant ranges and even well beyond. |
Databáze: | OpenAIRE |
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