SARS-CoV-2 Infection and C-Section: A Prospective Observational Study
| Autor: | E. Antolin, Maria Del Pilar Guadix Martin, María Begoña Encinas Pardilla, Laura Forcen Acebal, Oscar Martínez-Perez, José Antonio Sainz Bueno, José Román Broullón Molanes, Ana Álvarez Bartolomé, Juan Pedro Martínez Cendán, Pilar Pintado Recarte, Maria Luisa de la Cruz Conty |
|---|---|
| Přispěvatelé: | Materno-Infantil y Radiología, Universidad de Sevilla. Departamento de Cirugía, Instituto de Salud Carlos III |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Robson’s ten group Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) medicine.medical_treatment Gestational Age Comorbidity Asymptomatic Microbiology Article SARS-CoV-2 COVID-19 pregnancy delivery C-section perinatal outcomes pneumonia Young Adult Pregnancy Risk Factors Virology medicine Humans Prospective Studies Pregnancy Complications Infectious In vitro fertilisation business.industry Obstetrics Cesarean Section Infant Newborn Pregnancy Outcome Induction of labor Middle Aged medicine.disease QR1-502 Pneumonia Infectious Diseases Cohort Premature Birth Observational study Female Pregnancy Trimesters medicine.symptom business |
| Zdroj: | Viruses; Volume 13; Issue 11; Pages: 2330 Viruses Viruses 2021, 13(11), 2330 Viruses, Vol 13, Iss 2330, p 2330 (2021) RODIN. Repositorio de Objetos de Docencia e Investigación de la Universidad de Cádiz instname |
| ISSN: | 1999-4915 |
| DOI: | 10.3390/v13112330 |
| Popis: | Pregnant women are particularly vulnerable to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. In addition to unfavorable perinatal outcomes, there has been an increase in obstetric interventions. With this study, we aimed to clarify the reasons, using Robson's classification model, and risk factors for cesarean section (C-section) in SARS-CoV-2-infected mothers and their perinatal results. This was a prospective observational study that was carried out in 79 hospitals (Spanish Obstetric Emergency Group) with a cohort of 1704 SARS-CoV-2 PCR-positive pregnant women that were registered consecutively between 26 February and 5 November 2020. The data from 1248 pregnant women who delivered vaginally (vaginal + operative vaginal) was compared with those from 456 (26.8%) who underwent a C-section. C-section patients were older with higher rates of comorbidities, in vitro fertilization and multiple pregnancies (p < 0.05) compared with women who delivered vaginally. Moreover, C-section risk was associated with the presence of pneumonia (p < 0.001) and 41.1% of C-sections in patients with pneumonia were preterm (Robson's 10th category). However, delivery care was similar between asymptomatic and mild-moderate symptomatic patients (p = 0.228) and their predisposing factors to C-section were the presence of uterine scarring (due to a previous C-section) and the induction of labor or programmed C-section for unspecified obstetric reasons. On the other hand, higher rates of hemorrhagic events, hypertensive disorders and thrombotic events were observed in the C-section group (p < 0.001 for all three outcomes), as well as for ICU admission. These findings suggest that this type of delivery was associated with the mother's clinical conditions that required a rapid and early termination of pregnancy. This project was supported by public funds that were obtained in competitive calls: Grant COV20/00021 (EUR 43,000 from the Instituto de Salud Carlos III-Spanish Ministry of Health) and co-financed with Fondo Europeo de Desarrollo Regional (FEDER) funds. |
| Databáze: | OpenAIRE |
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