Low physical activity is a determinant for elevated blood pressure in high cardiovascular risk obstructive sleep apnea
| Autor: | Monique Mendelson, Patrick Levy, Jean-Philippe Baguet, Laurent Moreau, Christian Koltes, Sonia Dias-Domingos, Patrice Flore, David Laplaud, Gilles De Lamberterie, Léonidas Chavez, F. Herengt, Renaud Tamisier, Jean-Louis Pépin |
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| Rok vydání: | 2013 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Male medicine.medical_specialty Evening Health Behavior Motor Activity Critical Care and Intensive Care Medicine Body Mass Index Risk Factors Internal medicine medicine Humans Obesity Prospective Studies Morning Aged Aged 80 and over Sleep Apnea Obstructive Framingham Risk Score business.industry Sleep apnea Actigraphy General Medicine Anthropometry Middle Aged medicine.disease respiratory tract diseases Obstructive sleep apnea Hypertension Physical therapy Female Sedentary Behavior business |
| Zdroj: | Respiratory care. 59(8) |
| ISSN: | 1943-3654 |
| Popis: | Obstructive sleep apnea (OSA) is associated with cardiovascular morbidity, including hypertension. Beyond the severity of nocturnal hypoxia, other factors such as metabolic abnormalities but also sedentary behaviors and insufficient physical activity may contribute to elevated blood pressure (BP). To clarify the respective role of these factors as determinants of BP in OSA patients, we examined the relationship between BP and anthropometrics, severity of sleep apnea, and objectively measured physical activity and sedentary behaviors.Ninety-five adults presenting with OSA (apnea-hypopnea index10 events/h) and high cardiovascular risk (63.3 ± 8.8 y; body mass index: 29.9 ± 4.9 kg/m(2); apnea-hypopnea index: 41.3 ± 17.5/h; cardiovascular risk score: 13.5 ± 3.7%) were included. Physical activity and sedentary behaviors were objectively assessed by actigraphy, and self-measured home BP monitoring was measured. Logistic regression models adjusted for sex, age, and body mass index were built to identify the predictors of self-measured morning and evening BP.Physical activity was significantly related to obesity but not to the severity of sleep apnea or sleepiness. Sedentary behaviors were associated with self-measured morning and evening systolic BP (r = 0.32, P = .002; r = 0.29, P = .004). Steps per day were inversely associated with evening BP (r = -0.27, P = .01). Univariate analysis identified steps/d and time spent in vigorous physical activity as determinants for evening self-measured BP. In multivariate analysis, only steps/d were identified as a significant determinant of evening BP.Physical activity is the major determinant for evening BP in adults with OSA presenting high cardiovascular risk. Our results emphasize the need for lifestyle counseling programs in combination with CPAP to encourage regular physical activity in OSA subjects to obtain better BP control. (ClinicalTrials.gov registration NCT01226641.) |
| Databáze: | OpenAIRE |
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