Effect of probiotic on mast cell density and expression of tryptase, chymase, and TNF-α in the urinary bladder of rats with high cholesterol
| Autor: | Tuğrul Ertuğrul, Gulay Ciftci, Şerife Tütüncü |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Urinary bladder General Veterinary biology Chemistry Chymase Tryptase medicine.disease Mast cell High cholesterol law.invention Probiotic medicine.anatomical_structure Endocrinology Veterinary law Internal medicine biology.protein medicine Veteriner Hekimlik Animal Science and Zoology Tumor necrosis factor alpha Bladder high cholesterol mast cell probiotic TNF-alpha |
| Zdroj: | Volume: 69, Issue: 3 273-280 Ankara Üniversitesi Veteriner Fakültesi Dergisi |
| ISSN: | 1308-2817 |
| Popis: | In this study, it was aimed to immunohistochemically evaluate the possible effect of probiotic supplementation on rats fed a high cholesterol diet on mast cell heterogeneity and density in the urinary bladder and on the expression of chymase, tryptase and tumor necrosis factor-alpha (TNF-α) cytokine in the urinary bladder. Three groups were formed in the study. For 8 weeks, Group 1 (control group) was fed regular rat diet. Food for Group 2 (feeding +2% cholesterol) (high cholestrol group) was provided for 8 weeks. For the last four weeks, Group 3 (%2 cholesterol + Lactobacillus acidophilus) (probiotic group) was administered L. acidophilus probiotics. Levels of total cholesterol (TC) was measured by using a spectrophotometric autoanalyzer. Serum TC levels were remarkably increased in group 2 compared to the group 1 (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|