Diagnostic accuracy of white cell count and C-reactive protein for assessing the severity of paediatric appendicitis

Autor: Gandra Harinath, Paramita Baruah, Khurram Siddique, Santosh Bhandari, Shirin Mirza
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: JRSM Short Reports
ISSN: 2042-5333
Popis: Objectives Simple investigations like white cell count (WCC) and C-reactive protein (CRP) may help to improve the accuracy of diagnosis in paediatric appendicitis. We evaluated the diagnostic accuracy of WCC and CRP for the severity of acute appendicitis in children. Design Cross-sectional study. Setting This study was conducted on all children who underwent open appendectomy from January 2007 to December 2008 at a District General Hospital. Data regarding demographics, WCC, CRP, histology and postoperative complications were analysed. Participants All children who underwent open appendectomy during the study period. Main outcome measures Diagnostic accuracy of WCC and CRP for simple acute appendicitis and a perforated appendix. Results Out of 204 patients, 112 (54.9%) were girls. At surgery, appendix was grossly inflamed in 175 of which 32 had perforation. Histology revealed simple acute appendicitis in 135 (66.2%) and gangrenous appendicitis in 32 (15.7%). The rest were normal. The duration of symptoms, temperature, length of stay, WCC and CRP were significantly worse in the perforated group ( P value Conclusion Accuracy of WCC is higherthan CRP for diagnosing simple acute appendicitis. The combined sensitivity of WCC and CRP increases for simple acute appendicitis as well as a perforated appendix.
Databáze: OpenAIRE