Ivermectin, a new broad-spectrum antiparasitic agent
Autor: | M. H. Fisher, William C. Campbell, Egerton, P. Eskola, Mary F. Woods, Helmut Mrozik, John C. Chabala, R. L. Tolman, Dan A. Ostlind, L. H. Peterson, Aino Lusi |
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Rok vydání: | 1980 |
Předmět: |
Anthelmintics
Drug Ivermectin Sheep Chemistry media_common.quotation_subject Helminthiasis Disaccharides Antiparasitic agent Combinatorial chemistry Lactones Avermectin B1 Broad spectrum Drug Discovery medicine Animals Molecular Medicine Cattle Intestinal Diseases Parasitic media_common medicine.drug |
Zdroj: | Journal of Medicinal Chemistry. 23:1134-1136 |
ISSN: | 1520-4804 0022-2623 |
Popis: | 22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals. |
Databáze: | OpenAIRE |
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