Long-term immunogenicity of single dose of live attenuated hepatitis A vaccine in Indian children
| Autor: | Amita Sapru, Ashish Bavdekar, Amey Mane, Sheila Bhave, Vaibhavi Kapatkar |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Adolescent Hepatitis A vaccine India chemical and pharmacologic phenomena Hepatitis A Antibodies Vaccines Attenuated complex mixtures Young Adult Humans Medicine Child Hepatitis A Vaccines business.industry Maternal and child health Immunogenicity Follow up studies Infant Hepatitis A biochemical phenomena metabolism and nutrition medicine.disease Virology Hepatitis A antibody Immunization Child Preschool Pediatrics Perinatology and Child Health Immunology business Follow-Up Studies |
| Zdroj: | Indian Pediatrics. 52:687-690 |
| ISSN: | 0974-7559 0019-6061 |
| DOI: | 10.1007/s13312-015-0697-8 |
| Popis: | To assess immunogenicity of a single dose of live attenuated hepatitis A vaccine in Indian children, ten years after immunization.Of 143 children vaccinated in 2004, 121 children were evaluated in 2014, clinically and for anti-HAV antibodies.13 children were early vaccine failures who received two doses of HAV vaccine subsequently. 106 (98%) of 108 remaining children had seroprotective levels with a geometric mean titer of 100.5 mIU/mL. On analysis of all 121 children, the immunogenicity was 87.6%.Single dose of live attenuated hepatitis A vaccine provides long-term immunity in Indian children. |
| Databáze: | OpenAIRE |
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